AccelStab
Accelerated Stability Kinetic Modelling
Estimate the Šesták–Berggren kinetic model (degradation model) from experimental data. A closed-form (analytic) solution to the degradation model is implemented as a non-linear fit, allowing for the extrapolation of the degradation of a drug product - both in time and temperature. Parametric bootstrap, with kinetic parameters drawn from the multivariate t-distribution, and analytical formulae (the delta method) are available options to calculate the confidence and prediction intervals. The results (modelling, extrapolations and statistical intervals) can be visualised with multiple plots. The examples illustrate the accelerated stability modelling in drugs and vaccines development.
- Version2.1.1
- R versionR (≥ 4.1.0)
- LicenseAGPL (≥ 3)
- Needs compilation?No
- Languageen-GB
- Last release01/20/2025
Documentation
Team
Ben Wells
MaintainerShow author detailsAlex Ball
Show author detailsRolesContributorBernard G Franq
Show author detailsRolesAuthor, Copyright holderDaniel Williams
Show author detailsRolesContributor
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Last 30 days
This package has been downloaded 287 times in the last 30 days. Now we're getting somewhere! Enough downloads to populate a lively group chat. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 9 times.
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Last 365 days
This package has been downloaded 3,662 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Aug 28, 2024 with 59 downloads.
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Dependencies
- Imports5 packages
- Suggests4 packages