AccelStab

Accelerated Stability Kinetic Modelling

CRAN Package

Estimate the Šesták–Berggren kinetic model (degradation model) from experimental data. A closed-form (analytic) solution to the degradation model is implemented as a non-linear fit, allowing for the extrapolation of the degradation of a drug product - both in time and temperature. Parametric bootstrap, with kinetic parameters drawn from the multivariate t-distribution, and analytical formulae (the delta method) are available options to calculate the confidence and prediction intervals. The results (modelling, extrapolations and statistical intervals) can be visualised with multiple plots. The examples illustrate the accelerated stability modelling in drugs and vaccines development.

  • Version2.1.1
  • R versionR (≥ 4.1.0)
  • LicenseAGPL (≥ 3)
  • Needs compilation?No
  • Languageen-GB
  • Last release01/20/2025

Documentation


Team


Insights

Last 30 days

This package has been downloaded 287 times in the last 30 days. Now we're getting somewhere! Enough downloads to populate a lively group chat. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 9 times.

Sun
Mon
Tue
Wed
Thu
Fri
Sat
0 downloadsMar 2, 2025
13 downloadsMar 3, 2025
17 downloadsMar 4, 2025
26 downloadsMar 5, 2025
11 downloadsMar 6, 2025
13 downloadsMar 7, 2025
1 downloadsMar 8, 2025
4 downloadsMar 9, 2025
6 downloadsMar 10, 2025
14 downloadsMar 11, 2025
11 downloadsMar 12, 2025
6 downloadsMar 13, 2025
7 downloadsMar 14, 2025
16 downloadsMar 15, 2025
6 downloadsMar 16, 2025
7 downloadsMar 17, 2025
5 downloadsMar 18, 2025
5 downloadsMar 19, 2025
17 downloadsMar 20, 2025
14 downloadsMar 21, 2025
7 downloadsMar 22, 2025
14 downloadsMar 23, 2025
8 downloadsMar 24, 2025
9 downloadsMar 25, 2025
6 downloadsMar 26, 2025
10 downloadsMar 27, 2025
13 downloadsMar 28, 2025
2 downloadsMar 29, 2025
6 downloadsMar 30, 2025
4 downloadsMar 31, 2025
9 downloadsApr 1, 2025
0 downloadsApr 2, 2025
0 downloadsApr 3, 2025
0 downloadsApr 4, 2025
0 downloadsApr 5, 2025
1
26

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 3,662 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Aug 28, 2024 with 59 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Imports5 packages
  • Suggests4 packages