ApplyPolygenicScore
Utilities for the Application of a Polygenic Score to a VCF
Simple and transparent parsing of genotype/dosage data from an input Variant Call Format (VCF) file, matching of genotype coordinates to the component Single Nucleotide Polymorphisms (SNPs) of an existing polygenic score (PGS), and application of SNP weights to dosages for the calculation of a polygenic score for each individual in accordance with the additive weighted sum of dosages model. Methods are designed in reference to best practices described by Collister, Liu, and Clifton (2022) doi:10.3389/fgene.2022.818574.
- Version3.0.1
- R versionR (≥ 4.2.0)
- LicenseGPL-2
- Needs compilation?No
- Last release03/05/2025
Documentation
Team
Paul Boutros
MaintainerShow author detailsNicole Zeltser
Rachel Dang
Show author detailsRolesContributor
Insights
Last 30 days
This package has been downloaded 153 times in the last 30 days. Enough downloads to make a small wave in the niche community. The curiosity is spreading! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 18 times.
The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.
Last 365 days
This package has been downloaded 153 times in the last 365 days. More than a random curiosity, but not quite a blockbuster. Still, it's gaining traction! The day with the most downloads was Mar 08, 2025 with 45 downloads.
The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.
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Dependencies
- Imports6 packages
- Suggests3 packages