BIGL
Biochemically Intuitive Generalized Loewe Model
Response surface methods for drug synergy analysis. Available methods include generalized and classical Loewe formulations as well as Highest Single Agent methodology. Response surfaces can be plotted in an interactive 3-D plot and formal statistical tests for presence of synergistic effects are available. Implemented methods and tests are described in the article "BIGL: Biochemically Intuitive Generalized Loewe null model for prediction of the expected combined effect compatible with partial agonism and antagonism" by Koen Van der Borght, Annelies Tourny, Rytis Bagdziunas, Olivier Thas, Maxim Nazarov, Heather Turner, Bie Verbist & Hugo Ceulemans (2017)
- Version1.9.3
- R version≥ 3.5
- LicenseGPL-3
- Needs compilation?No
- Last release08/01/2024
Documentation
Team
Kathy Mutambanengwe
Heather Turner
Show author detailsRolesAuthorAnnelies Tourny
Show author detailsRolesAuthorOlivier Thas
Show author detailsRolesAuthorMaxim Nazarov
Show author detailsRolesAuthorRytis Bagdziunas
Show author detailsRolesAuthorStijn Hawinkel
Show author detailsRolesAuthorJavier Franco Pérez
Show author detailsRolesAuthor
Insights
Last 30 days
Last 365 days
The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.
Data provided by CRAN
Binaries
Dependencies
- Depends1 package
- Imports15 packages
- Suggests5 packages