BeviMed

Bayesian Evaluation of Variant Involvement in Mendelian Disease

CRAN Package

A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 doi:10.1016/j.ajhg.2017.05.015.


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