CPCAT

P-values and no/lowest observed (adverse) effect concentration values derived from the closure principle computational approach test (Lehmann, R. et al. (2015) doi:10.1007/s00477-015-1079-4) are provided. The package contains functions to generate intersection hypotheses according to the closure principle (Bretz, F., Hothorn, T., Westfall, P. (2010) doi:10.1201/9781420010909), an implementation of the computational approach test (Ching-Hui, C., Nabendu, P., Jyh-Jiuan, L. (2010) doi:10.1080/03610918.2010.508860) and the combination of both, that is, the closure principle computational approach test.

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