ComBatFamQC

Comprehensive Batch Effect Diagnostics and Harmonization

CRAN Package

Provides a comprehensive framework for batch effect diagnostics, harmonization, and post-harmonization downstream analysis. Features include interactive visualization tools, robust statistical tests, and a range of harmonization techniques. Additionally, 'ComBatFamQC' enables the creation of life-span age trend plots with estimated age-adjusted centiles and facilitates the generation of covariate-corrected residuals for analytical purposes. Methods for harmonization are based on approaches described in Johnson et al., (2007) doi:10.1093/biostatistics/kxj037, Beer et al., (2020) doi:10.1016/j.neuroimage.2020.117129, Pomponio et al., (2020) doi:10.1016/j.neuroimage.2019.116450, and Chen et al., (2021) doi:10.1002/hbm.25688.

  • Version1.0.5
  • R versionR (≥ 4.1.0)
  • LicenseMIT
  • Needs compilation?No
  • Languageen-US
  • Last releaselast Monday at 12:00 AM

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  • Imports19 packages
  • Suggests8 packages