CpmERCCutoff

Calculation of Log2 Counts per Million Cutoff from ERCC Controls

CRAN Package

Implementation of the empirical method to derive log2 counts per million (CPM) cutoff to filter out lowly expressed genes using ERCC spike-ins as described in Goll and Bosinger et.al (2022). This package utilizes the synthetic mRNA control pairs developed by the External RNA Controls Consortium (ERCC) (ERCC 1 / ERCC 2) that are spiked into sample pairs at known ratios at various absolute abundances. The relationship between the observed and expected fold changes is then used to empirically determine an optimal log2 CPM cutoff for filtering out lowly expressed genes.

  • Version1.0.0
  • R version≥ 3.6
  • LicenseGPL (≥ 3)
  • Needs compilation?No
  • Languageen-US
  • Last release09/13/2022

Team

Insights

Last 30 days

Last 365 days

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN

Binaries

Dependencies

  • Depends1 package
  • Imports2 packages
  • Suggests2 packages