DEploid

Deconvolute Mixed Genomes with Unknown Proportions

CRAN Package

Traditional phasing programs are limited to diploid organisms. Our method modifies Li and Stephens algorithm with Markov chain Monte Carlo (MCMC) approaches, and builds a generic framework that allows haplotype searches in a multiple infection setting. This package is primarily developed as part of the Pf3k project, which is a global collaboration using the latest sequencing technologies to provide a high-resolution view of natural variation in the malaria parasite Plasmodium falciparum. Parasite DNA are extracted from patient blood sample, which often contains more than one parasite strain, with unknown proportions. This package is used for deconvoluting mixed haplotypes, and reporting the mixture proportions from each sample.


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Insights

Last 30 days

This package has been downloaded 332 times in the last 30 days. More than a random curiosity, but not quite a blockbuster. Still, it's gaining traction! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 29 times.

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0 downloadsFeb 9, 2025
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4 downloadsFeb 14, 2025
26 downloadsFeb 15, 2025
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32 downloadsFeb 20, 2025
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17 downloadsMar 1, 2025
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7 downloadsMar 14, 2025
29 downloadsMar 15, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 2,381 times in the last 365 days. That's enough downloads to impress a room full of undergrads. A commendable achievement indeed. The day with the most downloads was Dec 26, 2024 with 45 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


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Dependencies

  • Imports6 packages
  • Suggests2 packages
  • Linking To1 package