DiscreteQvalue

Improved q-Values for Discrete Uniform and Homogeneous Tests

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We consider a multiple testing procedure used in many modern applications which is the q-value method proposed by Storey and Tibshirani (2003), . The q-value method is based on the false discovery rate (FDR), hence versions of the q-value method can be defined depending on which estimator of the proportion of true null hypotheses, p0, is plugged in the FDR estimator. We implement the q-value method based on two classical pi0 estimators, and furthermore, we propose and implement three versions of the q-value method for homogeneous discrete uniform P-values based on pi0 estimators which take into account the discrete distribution of the P-values.

  • Version1.1
  • R versionunknown
  • LicenseGPL-2
  • Needs compilation?No
  • Last release04/01/2020

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