DoseFinding
Planning and Analyzing Dose Finding Experiments
The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014) doi:10.1002/sim.6052).
- GitHub
- https://openpharma.github.io/DoseFinding/
- File a bug report
- DoseFinding results
- DoseFinding.pdf
- Version1.3-1
- R versionunknown
- LicenseGPL-3
- Needs compilation?Yes
- Last release03/11/2025
Documentation
- VignetteAnalysis template MCP-Mod for continuous data
- VignetteDesign and analysis template MCP-Mod for binary data
- VignetteFrequently Asked Questions for MCP-Mod
- VignetteAnalysis template: MCP-Mod with multiple regimen
- VignetteOverview DoseFinding package
- VignetteSample size template for MCP-Mod for normally distributed data
- MaterialREADME
- MaterialNEWS
- In ViewsClinicalTrials
- In ViewsExperimentalDesign
Team
Marius Thomas
MaintainerShow author detailsBjoern Bornkamp
Novartis Pharma AG
Show author detailsRolesCopyright holder, fndLudger Sandig
Show author detailsRolesAuthorJose Pinheiro
Show author detailsRolesAuthorFrank Bretz
Show author detailsRolesAuthor
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Dependencies
- Imports3 packages
- Suggests10 packages
- Reverse Depends2 packages
- Reverse Imports6 packages
- Reverse Suggests2 packages