DoseFinding
Planning and Analyzing Dose Finding Experiments
The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014) doi:10.1002/sim.6052).
- GitHub
- https://openpharma.github.io/DoseFinding/
- File a bug report
- DoseFinding results
- DoseFinding.pdf
- Version1.3-1
- R versionunknown
- LicenseGPL-3
- Needs compilation?Yes
- Last release03/11/2025
Documentation
- VignetteAnalysis template MCP-Mod for continuous data
- VignetteDesign and analysis template MCP-Mod for binary data
- VignetteFrequently Asked Questions for MCP-Mod
- VignetteAnalysis template: MCP-Mod with multiple regimen
- VignetteOverview DoseFinding package
- VignetteSample size template for MCP-Mod for normally distributed data
- MaterialREADME
- MaterialNEWS
- In ViewsClinicalTrials
- In ViewsExperimentalDesign
Team
Marius Thomas
MaintainerShow author detailsBjoern Bornkamp
Novartis Pharma AG
Show author detailsRolesCopyright holder, fndLudger Sandig
Show author detailsRolesAuthorJose Pinheiro
Show author detailsRolesAuthorFrank Bretz
Show author detailsRolesAuthor
Insights
Last 30 days
This package has been downloaded 2,426 times in the last 30 days. That's enough downloads to impress a room full of undergrads. A commendable achievement indeed. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 67 times.
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Last 365 days
This package has been downloaded 17,491 times in the last 365 days. The academic equivalent of having a dedicated subreddit. There are fans, and maybe even a few trolls! The day with the most downloads was Feb 12, 2025 with 255 downloads.
The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.
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Dependencies
- Imports3 packages
- Suggests10 packages
- Reverse Depends2 packages
- Reverse Imports6 packages
- Reverse Suggests2 packages