DoseFinding
Planning and Analyzing Dose Finding Experiments
The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014)
- Version1.2-1
- R versionunknown
- LicenseGPL-3
- Needs compilation?Yes
- Last release08/23/2024
Documentation
- VignetteAnalysis template MCP-Mod for continuous data
- Vignettesource
- VignetteR code
- VignetteDesign and analysis template MCP-Mod for binary data
- Vignettesource
- VignetteR code
- VignetteFrequently Asked Questions for MCP-Mod
- Vignettesource
- VignetteR code
- VignetteAnalysis template: MCP-Mod with multiple regimen
- Vignettesource
- VignetteR code
- VignetteOverview DoseFinding package
- Vignettesource
- VignetteR code
- VignetteSample size template for MCP-Mod for normally distributed data
- Vignettesource
- VignetteR code
- MaterialREADME
- MaterialNEWS
- In ViewsClinicalTrials
- In ViewsExperimentalDesign
Team
Marius Thomas
Bjoern Bornkamp
Jose Pinheiro
Show author detailsRolesAuthorFrank Bretz
Show author detailsRolesAuthorLudger Sandig
Show author detailsRolesAuthorNovartis Pharma AG
Show author detailsRolesCopyright holder, fnd
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- Imports3 packages
- Suggests11 packages
- Reverse Depends2 packages
- Reverse Imports7 packages
- Reverse Suggests1 package