MAPITR
MArginal ePIstasis Test for Regions
A genetic analysis tool and variance component model for identifying marginal epistasis between pathways and the rest of the genome. 'MAPITR' uses as input a matrix of genotypes, a vector of phenotypes, and a list of pathways. 'MAPITR' then iteratively tests each pathway for epistasis between any variants within the pathway versus any variants remaining in the rest of the genome. 'MAPITR' returns results in the form of p-values for every pathway indicating whether the null model of there being no epistatic interactions between a pathway and the rest of the genome can be rejected.
- Version1.1.2
- R version≥ 3.3.0
- LicenseMIT
- Licensefile LICENSE
- Needs compilation?Yes
- Last release09/28/2020
Documentation
Team
Michael Turchin
Gregory Darnell
Lorin Crawford
Sohini Ramachandran
Peter Carbonetto
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- Depends1 package
- Imports4 packages
- Suggests3 packages
- Linking To2 packages