MiRKAT

Microbiome Regression-Based Kernel Association Tests

CRAN Package

Test for overall association between microbiome composition data and phenotypes via phylogenetic kernels. The phenotype can be univariate continuous or binary (Zhao et al. (2015) doi:10.1016/j.ajhg.2015.04.003), survival outcomes (Plantinga et al. (2017) doi:10.1186/s40168-017-0239-9), multivariate (Zhan et al. (2017) doi:10.1002/gepi.22030) and structured phenotypes (Zhan et al. (2017) doi:10.1111/biom.12684). The package can also use robust regression (unpublished work) and integrated quantile regression (Wang et al. (2021) doi:10.1093/bioinformatics/btab668). In each case, the microbiome community effect is modeled nonparametrically through a kernel function, which can incorporate phylogenetic tree information.


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Insights

Last 30 days

This package has been downloaded 306 times in the last 30 days. Now we're getting somewhere! Enough downloads to populate a lively group chat. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 9 times.

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0 downloadsMar 2, 2025
0 downloadsMar 3, 2025
13 downloadsMar 4, 2025
26 downloadsMar 5, 2025
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9 downloadsMar 8, 2025
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13 downloadsMar 11, 2025
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31 downloadsMar 28, 2025
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3 downloadsMar 31, 2025
8 downloadsApr 1, 2025
9 downloadsApr 2, 2025
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0 downloadsApr 5, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 4,384 times in the last 365 days. Consider this 'mid-tier influencer' status—if it were a TikTok, it would get a nod from nieces and nephews. The day with the most downloads was Sep 11, 2024 with 62 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Imports10 packages
  • Suggests5 packages