OncoBayes2

Bayesian Logistic Regression for Oncology Dose-Escalation Trials

CRAN Package

Bayesian logistic regression model with optional EXchangeability-NonEXchangeability parameter modelling for flexible borrowing from historical or concurrent data-sources. The safety model can guide dose-escalation decisions for adaptive oncology Phase I dose-escalation trials which involve an arbitrary number of drugs. Please refer to Neuenschwander et al. (2008) doi:10.1002/sim.3230 and Neuenschwander et al. (2016) doi:10.1080/19466315.2016.1174149 for details on the methodology.


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