OneArm2stage

Phase II Single-Arm Two-Stage Designs with Time-to-Event Outcomes

CRAN Package

Two-stage design for single-arm phase II trials with time-to-event endpoints (e.g., clinical trials on immunotherapies among cancer patients) can be calculated using this package. Two notable advantages of the package: 1) It provides flexible choices from three design methods (optimal, minmax, and admissible), and 2) the power of the design is more accurately calculated using the exact variance in the one-sample log-rank test. The package can be used for 1) planning the sample sizes and other design parameters, and 2) conducting the interim and final analyses for the Go/No-go decisions. More details about the design method can be found in: Wu, J, Chen L, Wei J, Weiss H, Chauhan A. (2020). doi:10.1002/pst.1983.

  • Version1.2.1
  • R version≥ 3.5.0
  • LicenseGPL (≥ 3)
  • Needs compilation?No
  • Last release10/09/2023

Documentation


Team


Insights

Last 30 days

This package has been downloaded 193 times in the last 30 days. More than a random curiosity, but not quite a blockbuster. Still, it's gaining traction! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 5 times.

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0 downloadsMar 2, 2025
0 downloadsMar 3, 2025
13 downloadsMar 4, 2025
9 downloadsMar 5, 2025
4 downloadsMar 6, 2025
3 downloadsMar 7, 2025
5 downloadsMar 8, 2025
2 downloadsMar 9, 2025
3 downloadsMar 10, 2025
15 downloadsMar 11, 2025
4 downloadsMar 12, 2025
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5 downloadsMar 19, 2025
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10 downloadsMar 28, 2025
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5 downloadsMar 31, 2025
10 downloadsApr 1, 2025
5 downloadsApr 2, 2025
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0 downloadsApr 5, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 2,643 times in the last 365 days. Consider this 'mid-tier influencer' status—if it were a TikTok, it would get a nod from nieces and nephews. The day with the most downloads was Jan 21, 2025 with 33 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


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Dependencies

  • Imports3 packages
  • Suggests3 packages