PLEXI

Multiplex Network Analysis

CRAN Package

Interactions between different biological entities are crucial for the function of biological systems. In such networks, nodes represent biological elements, such as genes, proteins and microbes, and their interactions can be defined by edges, which can be either binary or weighted. The dysregulation of these networks can be associated with different clinical conditions such as diseases and response to treatments. However, such variations often occur locally and do not concern the whole network. To capture local variations of such networks, we propose multiplex network differential analysis (MNDA). MNDA allows to quantify the variations in the local neighborhood of each node (e.g. gene) between the two given clinical states, and to test for statistical significance of such variation. Yousefi et al. (2023) doi:10.1101/2023.01.22.525058.


Team


Insights

Last 30 days

This package has been downloaded 168 times in the last 30 days. More than a random curiosity, but not quite a blockbuster. Still, it's gaining traction! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 12 times.

Sun
Mon
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Sat
3 downloadsMar 9, 2025
3 downloadsMar 10, 2025
11 downloadsMar 11, 2025
6 downloadsMar 12, 2025
5 downloadsMar 13, 2025
3 downloadsMar 14, 2025
4 downloadsMar 15, 2025
3 downloadsMar 16, 2025
1 downloadsMar 17, 2025
9 downloadsMar 18, 2025
4 downloadsMar 19, 2025
10 downloadsMar 20, 2025
6 downloadsMar 21, 2025
4 downloadsMar 22, 2025
5 downloadsMar 23, 2025
6 downloadsMar 24, 2025
6 downloadsMar 25, 2025
2 downloadsMar 26, 2025
8 downloadsMar 27, 2025
3 downloadsMar 28, 2025
1 downloadsMar 29, 2025
11 downloadsMar 30, 2025
3 downloadsMar 31, 2025
2 downloadsApr 1, 2025
5 downloadsApr 2, 2025
12 downloadsApr 3, 2025
5 downloadsApr 4, 2025
3 downloadsApr 5, 2025
12 downloadsApr 6, 2025
12 downloadsApr 7, 2025
0 downloadsApr 8, 2025
0 downloadsApr 9, 2025
0 downloadsApr 10, 2025
0 downloadsApr 11, 2025
0 downloadsApr 12, 2025
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12

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 1,847 times in the last 365 days. That's enough downloads to impress a room full of undergrads. A commendable achievement indeed. The day with the most downloads was Jan 21, 2025 with 21 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Imports6 packages