CRAN/E | SCAT

SCAT

Summary Based Conditional Association Test

Installation

About

Conditional association test based on summary data from genome-wide association study (GWAS). SCAT adjusts for heterogeneity in SNP coverage that exists in summary data if SNPs are not present in all of the participating studies of a GWAS meta-analysis. This commonly happens when different reference panels are used in participating studies for genotype imputation. This could happen when ones simply do not have data for some SNPs (e.g. different array, or imputated data is not available). Without properly adjusting for this kind of heterogeneity leads to inflated false positive rate. SCAT can also be used to conduct conventional conditional analysis when coverage heterogeneity is absent. For more details, refer to Zhang et al. (2018) Brief Bioinform. 19(6):1337-1343. doi:10.1093/bib/bbx072.

System requirements C++11

Key Metrics

Version 0.5.0
Published 2019-02-01 1959 days ago
Needs compilation? yes
License GPL-2
License GPL-3
CRAN checks SCAT results

Downloads

Yesterday 0
Last 7 days 0 -100%
Last 30 days 17 -15%
Last 90 days 72 -34%
Last 365 days 330 -84%

Maintainer

Maintainer

Han Zhang

Authors

Han Zhang
Kai Yu

Material

README
Reference manual
Package source

In Views

MissingData

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

SCAT archive

Depends

stats
utils