SeqKat
Detection of Kataegis
Kataegis is a localized hypermutation occurring when a region is enriched in somatic SNVs. Kataegis can result from multiple cytosine deaminations catalyzed by the AID/APOBEC family of proteins. This package contains functions to detect kataegis from SNVs in BED format. This package reports two scores per kataegic event, a hypermutation score and an APOBEC mediated kataegic score. Yousif, F. et al.; The Origins and Consequences of Localized and Global Somatic Hypermutation; Biorxiv 2018 doi:10.1101/287839.
- Version0.0.8
- R versionunknown
- LicenseGPL-2
- Needs compilation?Yes
- Last release03/11/2020
Documentation
Team
Fouad Yousif
Xihui Lin
Fan Fan
Christopher Lalansingh
John Macdonald
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- Depends2 packages
- Imports1 package
- Suggests4 packages
- Linking To1 package