SubgrpID

Patient Subgroup Identification for Clinical Drug Development

CRAN Package

Implementation of Sequential BATTing (bootstrapping and aggregating of thresholds from trees) for developing threshold-based multivariate (prognostic/predictive) biomarker signatures. Variable selection is automatically built-in. Final signatures are returned with interaction plots for predictive signatures. Cross-validation performance evaluation and testing dataset results are also output. Detail algorithms are described in Huang et al (2017) doi:10.1002/sim.7236.


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  • Imports6 packages