ThreeArmedTrials

Design and Analysis of Clinical Non-Inferiority or Superiority Trials with Active and Placebo Control

CRAN Package

Design and analyze three-arm non-inferiority or superiority trials which follow a gold-standard design, i.e. trials with an experimental treatment, an active, and a placebo control. Method for the following distributions are implemented: Poisson (Mielke and Munk (2009) ), negative binomial (Muetze et al. (2016) ), normal (Pigeot et al. (2003) ; Hasler et al. (2009) ), binary (Friede and Kieser (2007) ), nonparametric (Muetze et al. (2017) ), exponential (Mielke and Munk (2009) ).


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