TopDom

An Efficient and Deterministic Method for Identifying Topological Domains in Genomes

CRAN Package

The 'TopDom' method identifies topological domains in genomes from Hi-C sequence data (Shin et al., 2016 doi:10.1093/nar/gkv1505). The authors published an implementation of their method as an R script (two different versions; also available in this package). This package originates from those original 'TopDom' R scripts and provides help pages adopted from the original 'TopDom' PDF documentation. It also provides a small number of bug fixes to the original code.


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