aphid
Analysis with Profile Hidden Markov Models
Designed for the development and application of hidden Markov models and profile HMMs for biological sequence analysis. Contains functions for multiple and pairwise sequence alignment, model construction and parameter optimization, file import/export, implementation of the forward, backward and Viterbi algorithms for conditional sequence probabilities, tree-based sequence weighting, and sequence simulation. Features a wide variety of potential applications including database searching, gene-finding and annotation, phylogenetic analysis and sequence classification. Based on the models and algorithms described in Durbin et al (1998, ISBN: 9780521629713).
- Version1.3.5
- R version≥ 3.0.0
- LicenseGPL-3
- Needs compilation?Yes
- aphid citation info
- Last release12/05/2022
Documentation
Team
Shaun Wilkinson
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- Depends1 package
- Imports4 packages
- Suggests5 packages
- Linking To1 package
- Reverse Imports3 packages