apmx

Automated methods to assemble population PK (pharmacokinetic) and PKPD (pharmacodynamic) datasets for analysis in 'NONMEM' (non-linear mixed effects modeling) by Bauer (2019) doi:10.1002/psp4.12404. The package includes functions to build datasets from SDTM (study data tabulation module) https://www.cdisc.org/standards/foundational/sdtm, ADaM (analysis dataset module) https://www.cdisc.org/standards/foundational/adam, or other dataset formats. The package will combine population datasets, add covariates, and create documentation to support regulatory submission and internal communication.

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