babelgene

Gene Orthologs for Model Organisms in a Tidy Data Format

CRAN Package

Genomic analysis of model organisms frequently requires the use of databases based on human data or making comparisons to patient-derived resources. This requires harmonization of gene names into the same gene space. The 'babelgene' R package converts between human and non-human gene orthologs/homologs. The package integrates orthology assertion predictions sourced from multiple databases as compiled by the HGNC Comparison of Orthology Predictions (HCOP) (Wright et al. 2005 doi:10.1007/s00335-005-0103-2, Eyre et al. 2007 doi:10.1093/bib/bbl030, Seal et al. 2011 doi:10.1093/nar/gkq892).


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