blindrecalc

Blinded Sample Size Recalculation

CRAN Package

Computation of key characteristics and plots for blinded sample size recalculation. Continuous as well as binary endpoints are supported in superiority and non-inferiority trials. See Baumann, Pilz, Kieser (2022) doi:10.32614/RJ-2022-001 for a detailed description. The implemented methods include the approaches by Lu, K. (2019) doi:10.1002/pst.1737, Kieser, M. and Friede, T. (2000) doi:10.1002/(SICI)1097-0258(20000415)19:7<901::AID-SIM405>3.0.CO;2-L1097-0258(20000415)19:7%3C901::AID-SIM405%3E3.0.CO;2-L), Friede, T. and Kieser, M. (2004) doi:10.1002/pst.140, Friede, T., Mitchell, C., Mueller-Veltern, G. (2007) doi:10.1002/bimj.200610373, and Friede, T. and Kieser, M. (2011) doi:10.3414/ME09-01-0063.


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