calmate
Improved Allele-Specific Copy Number of SNP Microarrays for Downstream Segmentation
The CalMaTe method calibrates preprocessed allele-specific copy number estimates (ASCNs) from DNA microarrays by controlling for single-nucleotide polymorphism-specific allelic crosstalk. The resulting ASCNs are on average more accurate, which increases the power of segmentation methods for detecting changes between copy number states in tumor studies including copy neutral loss of heterozygosity. CalMaTe applies to any ASCNs regardless of preprocessing method and microarray technology, e.g. Affymetrix and Illumina.
- Version0.13.0
- R version≥ 3.2.1
- LicenseLGPL-2.1
- LicenseLGPL-3
- Needs compilation?No
- calmate citation info
- Last release03/08/2022
Documentation
Team
Henrik Bengtsson
Maria Ortiz
Show author detailsRolesAuthor, ContributorAnder Aramburu
Show author detailsRolesContributorPierre Neuvial
Show author detailsRolesAuthor, ContributorAngel Rubio
Show author detailsRolesAuthor, Contributor
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- Depends3 packages
- Imports6 packages
- Suggests1 package