caradpt

Tools for implementing covariate-adjusted response-adaptive procedures for binary, continuous and survival responses. Users can flexibly choose between two functions based on their specific needs for each procedure: use real patient data from clinical trials to compute allocation probabilities directly, or use built-in simulation functions to generate synthetic patient data. Detailed methodologies and algorithms used in this package are described in the following references: Zhang, L. X., Hu, F., Cheung, S. H., & Chan, W. S. (2007) Zhang, L. X. & Hu, F. (2009) Hu, J., Zhu, H., & Hu, F. (2015) Zhao, W., Ma, W., Wang, F., & Hu, F. (2022) Mukherjee, A., Jana, S., & Coad, S. (2024).

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