depower

Provides a convenient framework to simulate, test, power, and visualize data for differential expression studies with lognormal or negative binomial outcomes. Supported designs are two-sample comparisons of independent or dependent outcomes. Power may be summarized in the context of controlling the per-family error rate or family-wise error rate. Negative binomial methods are described in Yu, Fernandez, and Brock (2017) doi:10.1186/s12859-017-1648-2 and Yu, Fernandez, and Brock (2020) doi:10.1186/s12859-020-3541-7.

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