factorial2x2

Used for the design and analysis of a 2x2 factorial trial for a time-to-event endpoint. It performs power calculations and significance testing as well as providing estimates of the relevant hazard ratios and the corresponding 95% confidence intervals. Important reference papers include Slud EV. (1994) https://www.ncbi.nlm.nih.gov/pubmed/8086609 Lin DY, Gong J, Gallo P, Bunn PH, Couper D. (2016) doi:10.1111/biom.12507 Leifer ES, Troendle JF, Kolecki A, Follmann DA. (2020) https://github.com/EricSLeifer/factorial2x2/blob/master/Leifer%20et%20al.%20paper.pdf.

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