CRAN/E | famSKATRC

famSKATRC

Family Sequence Kernel Association Test for Rare and Common Variants

Installation

About

FamSKAT-RC is a family-based association kernel test for both rare and common variants. This test is general and several special cases are known as other methods: famSKAT, which only focuses on rare variants in family-based data, SKAT, which focuses on rare variants in population-based data (unrelated individuals), and SKAT-RC, which focuses on both rare and common variants in population-based data. When one applies famSKAT-RC and sets the value of phi to 1, famSKAT-RC becomes famSKAT. When one applies famSKAT-RC and set the value of phi to 1 and the kinship matrix to the identity matrix, famSKAT-RC becomes SKAT. When one applies famSKAT-RC and set the kinship matrix (fullkins) to the identity matrix (and phi is not equal to 1), famSKAT-RC becomes SKAT-RC. We also include a small sample synthetic pedigree to demonstrate the method with. For more details see Saad M and Wijsman EM (2014) doi:10.1002/gepi.21844.

www.r-project.org
www.ncbi.nlm.nih.gov/pubmed/25132070

Key Metrics

Version 1.1.0
R ≥ 3.4.1
Published 2017-11-09 2496 days ago
Needs compilation? no
License GPL (≥ 3)
CRAN checks famSKATRC results

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Maintainer

Maintainer

Khalid B. Kunji

Authors

Khalid B. Kunji

aut / cre

Mohamad Saad

aut

Material

Reference manual
Package source

macOS

r-release

arm64

r-oldrel

arm64

r-release

x86_64

r-oldrel

x86_64

Windows

r-devel

x86_64

r-release

x86_64

r-oldrel

x86_64

Old Sources

famSKATRC archive

Depends

R ≥ 3.4.1

Imports

CompQuadForm
kinship2
coxme
bdsmatrix

Reverse Imports

Mega2R