gJLS2

A Generalized Joint Location and Scale Framework for Association Testing

CRAN Package

An update to the Joint Location-Scale (JLS) testing framework that identifies associated SNPs, gene-sets and pathways with main and/or interaction effects on quantitative traits (Soave et al., 2015; doi:10.1016/j.ajhg.2015.05.015). The JLS method simultaneously tests the null hypothesis of equal mean and equal variance across genotypes, by aggregating association evidence from the individual location/mean-only and scale/variance-only tests using Fisher's method. The generalized joint location-scale (gJLS) framework has been developed to deal specifically with sample correlation and group uncertainty (Soave and Sun, 2017; doi:10.1111/biom.12651). The current release: gJLS2, include additional functionalities that enable analyses of X-chromosome genotype data through novel methods for location (Chen et al., 2021; doi:10.1002/gepi.22422) and scale (Deng et al., 2019; doi:10.1002/gepi.22247).

  • Version0.2.0
  • R version≥ 3.6.0
  • LicenseGPL (≥ 3)
  • Needs compilation?No
  • Last release09/30/2021

Documentation


Team


Insights

Last 30 days

This package has been downloaded 142 times in the last 30 days. Enough downloads to make a small wave in the niche community. The curiosity is spreading! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 4 times.

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4 downloadsApr 4, 2025
0 downloadsApr 5, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 2,018 times in the last 365 days. Consider this 'mid-tier influencer' status—if it were a TikTok, it would get a nod from nieces and nephews. The day with the most downloads was Sep 11, 2024 with 23 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Imports7 packages
  • Suggests2 packages