gJLS2

A Generalized Joint Location and Scale Framework for Association Testing

CRAN Package

An update to the Joint Location-Scale (JLS) testing framework that identifies associated SNPs, gene-sets and pathways with main and/or interaction effects on quantitative traits (Soave et al., 2015; doi:10.1016/j.ajhg.2015.05.015). The JLS method simultaneously tests the null hypothesis of equal mean and equal variance across genotypes, by aggregating association evidence from the individual location/mean-only and scale/variance-only tests using Fisher's method. The generalized joint location-scale (gJLS) framework has been developed to deal specifically with sample correlation and group uncertainty (Soave and Sun, 2017; doi:10.1111/biom.12651). The current release: gJLS2, include additional functionalities that enable analyses of X-chromosome genotype data through novel methods for location (Chen et al., 2021; doi:10.1002/gepi.22422) and scale (Deng et al., 2019; doi:10.1002/gepi.22247).

  • Version0.2.0
  • R version≥ 3.6.0
  • LicenseGPL (≥ 3)
  • Needs compilation?No
  • Last release09/30/2021

Documentation


Team


Insights

Last 30 days

This package has been downloaded 151 times in the last 30 days. Now we're getting somewhere! Enough downloads to populate a lively group chat. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 7 times.

Sun
Mon
Tue
Wed
Thu
Fri
Sat
0 downloadsMar 2, 2025
0 downloadsMar 3, 2025
9 downloadsMar 4, 2025
6 downloadsMar 5, 2025
3 downloadsMar 6, 2025
4 downloadsMar 7, 2025
3 downloadsMar 8, 2025
2 downloadsMar 9, 2025
3 downloadsMar 10, 2025
9 downloadsMar 11, 2025
4 downloadsMar 12, 2025
5 downloadsMar 13, 2025
3 downloadsMar 14, 2025
6 downloadsMar 15, 2025
1 downloadsMar 16, 2025
1 downloadsMar 17, 2025
12 downloadsMar 18, 2025
4 downloadsMar 19, 2025
11 downloadsMar 20, 2025
7 downloadsMar 21, 2025
3 downloadsMar 22, 2025
7 downloadsMar 23, 2025
8 downloadsMar 24, 2025
6 downloadsMar 25, 2025
4 downloadsMar 26, 2025
3 downloadsMar 27, 2025
5 downloadsMar 28, 2025
2 downloadsMar 29, 2025
6 downloadsMar 30, 2025
1 downloadsMar 31, 2025
6 downloadsApr 1, 2025
7 downloadsApr 2, 2025
0 downloadsApr 3, 2025
0 downloadsApr 4, 2025
0 downloadsApr 5, 2025
1
12

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 2,025 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Sep 11, 2024 with 23 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Imports7 packages
  • Suggests2 packages