grouprar

Group Response Adaptive Randomization for Clinical Trials

CRAN Package

Implement group response-adaptive randomization procedures, which also integrates standard non-group response-adaptive randomization methods as specialized instances. It is also uniquely capable of managing complex scenarios, including those with delayed and missing responses, thereby expanding its utility in real-world applications. This package offers 16 functions for simulating a variety of response adaptive randomization procedures. These functions are essential for guiding the selection of statistical methods in clinical trials, providing a flexible and effective approach to trial design. Some of the detailed methodologies and algorithms used in this package, please refer to the following references: LJ Wei (1979) L. J. WEI and S. DURHAM (1978) Durham, S. D., FlournoY, N. AND LI, W. (1998) Ivanova, A., Rosenberger, W. F., Durham, S. D. and Flournoy, N. (2000) Bai Z D, Hu F, Shen L. (2002) Ivanova, A. (2003) Hu, F., & Zhang, L. X. (2004) Hu, F., & Rosenberger, W. F. (2006, ISBN:978-0-471-65396-7). Zhang, L. X., Chan, W. S., Cheung, S. H., & Hu, F. (2007) Zhang, L., & Rosenberger, W. F. (2006) Hu, F., Zhang, L. X., Cheung, S. H., & Chan, W. S. (2008).


Team


Insights

Last 30 days

This package has been downloaded 146 times in the last 30 days. Now we're getting somewhere! Enough downloads to populate a lively group chat. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 9 times.

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0 downloadsMar 2, 2025
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9 downloadsMar 4, 2025
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9 downloadsApr 2, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 1,892 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Sep 03, 2024 with 23 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Imports5 packages