gsDesign2
Group Sequential Design with Non-Constant Effect
The goal of 'gsDesign2' is to enable fixed or group sequential design under non-proportional hazards. To enable highly flexible enrollment, time-to-event and time-to-dropout assumptions, 'gsDesign2' offers piecewise constant enrollment, failure rates, and dropout rates for a stratified population. This package includes three methods for designs: average hazard ratio, weighted logrank tests in Yung and Liu (2019) doi:10.1111/biom.13196, and MaxCombo tests. Substantial flexibility on top of what is in the 'gsDesign' package is intended for selecting boundaries.
- Version1.1.3
- R version≥ 3.5.0
- LicenseGPL-3
- Needs compilation?Yes
- Last release11/15/2024
Documentation
Team
Yujie Zhao
MaintainerShow author detailsYalin Zhu
Hongtao Zhang
Show author detailsRolesContributorNan Xiao
John Blischak
Show author detailsRolesContributorKeaven Anderson
Show author detailsRolesAuthorYilong Zhang
Show author detailsRolesAuthorJianxiao Yang
Show author detailsRolesAuthorHiroaki Fukuda
Show author detailsRolesContributorMerck & Co., Inc., Rahway, NJ, USA and its affiliates
Show author detailsRolesCopyright holderAmin Shirazi
Show author detailsRolesContributorRuixue Wang
Show author detailsRolesContributorYi Cui
Show author detailsRolesContributorPing Yang
Show author detailsRolesContributorXin Tong Li
Show author detailsRolesContributorChenxiang Li
Show author detailsRolesContributorDickson Wanjau
Show author detailsRolesContributor
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Dependencies
- Imports12 packages
- Suggests7 packages
- Linking To1 package
- Reverse Imports1 package