hacksig

A Tidy Framework to Hack Gene Expression Signatures

CRAN Package

A collection of cancer transcriptomics gene signatures as well as a simple and tidy interface to compute single sample enrichment scores either with the original procedure or with three alternatives: the "combined z-score" of Lee et al. (2008) doi:10.1371/journal.pcbi.1000217, the "single sample GSEA" of Barbie et al. (2009) doi:10.1038/nature08460 and the "singscore" of Foroutan et al. (2018) doi:10.1186/s12859-018-2435-4. The 'get_sig_info()' function can be used to retrieve information about each signature implemented.


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  • Imports5 packages
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