iDOS

Integrated Discovery of Oncogenic Signatures

CRAN Package

A method to integrate molecular profiles of cancer patients (gene copy number and mRNA abundance) to identify candidate gain of function alterations. These candidate alterations can be subsequently further tested to discover cancer driver alterations. Briefly, this method tests of genomic correlates of mRNA dysregulation and prioritise those where DNA gains/amplifications are associated with elevated mRNA expression of the same gene. For details see, Haider S et al. (2016) "Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia", Genome Biology, https://pubmed.ncbi.nlm.nih.gov/27358048/.

  • Version1.0.1
  • R versionunknown
  • LicenseGPL-2
  • Needs compilation?No
  • Last release03/11/2024

Documentation


Team


Insights

Last 30 days

This package has been downloaded 128 times in the last 30 days. More than a random curiosity, but not quite a blockbuster. Still, it's gaining traction! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 6 times.

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0 downloadsMar 2, 2025
0 downloadsMar 3, 2025
0 downloadsMar 4, 2025
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0 downloadsMar 8, 2025
2 downloadsMar 9, 2025
4 downloadsMar 10, 2025
5 downloadsMar 11, 2025
4 downloadsMar 12, 2025
3 downloadsMar 13, 2025
2 downloadsMar 14, 2025
6 downloadsMar 15, 2025
1 downloadsMar 16, 2025
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10 downloadsMar 18, 2025
3 downloadsMar 19, 2025
12 downloadsMar 20, 2025
7 downloadsMar 21, 2025
4 downloadsMar 22, 2025
6 downloadsMar 23, 2025
7 downloadsMar 24, 2025
2 downloadsMar 25, 2025
1 downloadsMar 26, 2025
4 downloadsMar 27, 2025
11 downloadsMar 28, 2025
1 downloadsMar 29, 2025
11 downloadsMar 30, 2025
1 downloadsMar 31, 2025
4 downloadsApr 1, 2025
4 downloadsApr 2, 2025
0 downloadsApr 3, 2025
3 downloadsApr 4, 2025
3 downloadsApr 5, 2025
6 downloadsApr 6, 2025
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0 downloadsApr 11, 2025
0 downloadsApr 12, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 2,061 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Jul 21, 2024 with 69 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Depends1 package