idem

Inference in Randomized Controlled Trials with Death and Missingness

CRAN Package

In randomized studies involving severely ill patients, functional outcomes are often unobserved due to missed clinic visits, premature withdrawal or death. It is well known that if these unobserved functional outcomes are not handled properly, biased treatment comparisons can be produced. In this package, we implement a procedure for comparing treatments that is based on the composite endpoint of both the functional outcome and survival. The procedure was proposed in Wang et al. (2016) doi:10.1111/biom.12594 and Wang et al. (2020) doi:10.18637/jss.v093.i12. It considers missing data imputation with different sensitivity analysis strategies to handle the unobserved functional outcomes not due to death.


Documentation


Team


Insights

Last 30 days

This package has been downloaded 326 times in the last 30 days. More than a random curiosity, but not quite a blockbuster. Still, it's gaining traction! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 24 times.

Sun
Mon
Tue
Wed
Thu
Fri
Sat
0 downloadsFeb 9, 2025
0 downloadsFeb 10, 2025
0 downloadsFeb 11, 2025
0 downloadsFeb 12, 2025
0 downloadsFeb 13, 2025
15 downloadsFeb 14, 2025
13 downloadsFeb 15, 2025
5 downloadsFeb 16, 2025
15 downloadsFeb 17, 2025
5 downloadsFeb 18, 2025
18 downloadsFeb 19, 2025
42 downloadsFeb 20, 2025
6 downloadsFeb 21, 2025
5 downloadsFeb 22, 2025
13 downloadsFeb 23, 2025
7 downloadsFeb 24, 2025
3 downloadsFeb 25, 2025
5 downloadsFeb 26, 2025
21 downloadsFeb 27, 2025
3 downloadsFeb 28, 2025
13 downloadsMar 1, 2025
11 downloadsMar 2, 2025
7 downloadsMar 3, 2025
13 downloadsMar 4, 2025
22 downloadsMar 5, 2025
4 downloadsMar 6, 2025
7 downloadsMar 7, 2025
5 downloadsMar 8, 2025
2 downloadsMar 9, 2025
3 downloadsMar 10, 2025
17 downloadsMar 11, 2025
4 downloadsMar 12, 2025
9 downloadsMar 13, 2025
9 downloadsMar 14, 2025
24 downloadsMar 15, 2025
2
42

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 3,867 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Sep 11, 2024 with 45 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Depends1 package
  • Imports6 packages
  • Suggests6 packages
  • Linking To6 packages