iq

Protein Quantification in Mass Spectrometry-Based Proteomics

CRAN Package

An implementation of the MaxLFQ algorithm by Cox et al. (2014) doi:10.1074/mcp.M113.031591 in a comprehensive pipeline for processing proteomics data in data-independent acquisition mode (Pham et al. 2020 doi:10.1093/bioinformatics/btz961). It offers additional options for protein quantification using the N most intense fragment ions, using all fragment ions, and a wrapper for the median polish algorithm by Tukey (1977, ISBN:0201076160). In general, the tool can be used to integrate multiple proportional observations into a single quantitative value.


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