markerpen

Marker Gene Detection via Penalized Principal Component Analysis

CRAN Package

Implementation of the 'MarkerPen' algorithm, short for marker gene detection via penalized principal component analysis, described in the paper by Qiu, Wang, Lei, and Roeder (2020, doi:10.1101/2020.11.07.373043). 'MarkerPen' is a semi-supervised algorithm for detecting marker genes by combining prior marker information with bulk transcriptome data.

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