markovMSM

The inference in multi-state models is traditionally performed under a Markov assumption that claims that past and future of the process are independent given the present state. In this package, we consider tests of the Markov assumption that are applicable to general multi-state models. Three approaches using existing methodology are considered: a simple method based on including covariates depending on the history in Cox models for the transition intensities; methods based on measuring the discrepancy of the non-Markov estimators of the transition probabilities to the Markov Aalen-Johansen estimators; and, finally, methods that were developed by considering summaries from families of log-rank statistics where patients are grouped by the state occupied of the process at a particular time point (see Soutinho G, Meira-Machado L (2021) doi:10.1007/s00180-021-01139-7 and Titman AC, Putter H (2020) doi:10.1093/biostatistics/kxaa030).

Last 30 days

This package has been downloaded 181 times in the last 30 days. Enough downloads to make a small wave in the niche community. The curiosity is spreading! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 9 times.

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Last 365 days

This package has been downloaded 3,261 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Jul 21, 2024 with 75 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.