mnda
Multiplex Network Differential Analysis (MNDA)
Interactions between different biological entities are crucial for the function of biological systems. In such networks, nodes represent biological elements, such as genes, proteins and microbes, and their interactions can be defined by edges, which can be either binary or weighted. The dysregulation of these networks can be associated with different clinical conditions such as diseases and response to treatments. However, such variations often occur locally and do not concern the whole network. To capture local variations of such networks, we propose multiplex network differential analysis (MNDA). MNDA allows to quantify the variations in the local neighborhood of each node (e.g. gene) between the two given clinical states, and to test for statistical significance of such variation. Yousefi et al. (2023) doi:10.1101/2023.01.22.525058.
- Version1.0.9
- R versionunknown
- LicenseGPL (≥ 3)
- Needs compilation?No
- Last release01/25/2023
Team
Behnam Yousefi
Farzaneh Firoozbakht
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Insights
Last 30 days
This package has been downloaded 186 times in the last 30 days. Enough downloads to make a small wave in the niche community. The curiosity is spreading! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 10 times.
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Last 365 days
This package has been downloaded 2,356 times in the last 365 days. That's enough downloads to impress a room full of undergrads. A commendable achievement indeed. The day with the most downloads was Sep 11, 2024 with 24 downloads.
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Dependencies
- Imports11 packages