nlmixr2est
Nonlinear Mixed Effects Models in Population PK/PD, Estimation Routines
Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 doi:10.1007/s10928-015-9409-1). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 doi:10.1002/psp4.12052).
- Version4.0.2
- R versionR (≥ 4.0)
- LicenseGPL (≥ 3)
- Needs compilation?Yes
- Languageen-US
- nlmixr2est citation info
- Last release07/25/2025
Documentation
Team
Matthew Fidler
MaintainerShow author detailsRik Schoemaker
Emmanuelle Comets
Show author detailsRolesContributorRichard Hooijmaijers
Show author detailsRolesAuthorDirk Eddelbuettel
Show author detailsRolesCopyright holderYuan Xiong
Show author detailsRolesAuthorJustin Wilkins
Ben Goodrich
Show author detailsRolesContributorMarc Lavielle
Show author detailsRolesContributorHadley Wickham
Show author detailsRolesContributorMirjam Trame
Show author detailsRolesContributorRobert Leary
Show author detailsRolesContributorVipul Mann
Show author detailsRolesAuthorJohannes Pfeifer
Show author detailsRolesContributorRobert B. Schnabel
Show author detailsRolesContributorWenping Wang
Show author detailsRolesAuthorKatharine Mullen
Show author detailsRolesCopyright holderElizabeth Eskow
Show author detailsRolesContributorMahmoud Abdelwahab
Show author detailsRolesContributorMason McComb
Teun Post
Show author detailsRolesContributorAudrey Lavenu
Show author detailsRolesContributorDavid Ardia
Show author detailsRolesCopyright holder
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Dependencies
- Depends1 package
- Imports15 packages
- Suggests17 packages
- Linking To8 packages
- Reverse Imports8 packages
- Reverse Suggests1 package