nlmixr2est
Nonlinear Mixed Effects Models in Population PK/PD, Estimation Routines
Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 doi:10.1007/s10928-015-9409-1). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 doi:10.1002/psp4.12052).
- Version3.0.4
- R version≥ 4.0
- LicenseGPL (≥ 3)
- Needs compilation?Yes
- Languageen-US
- nlmixr2est citation info
- Last release02/19/2025
Documentation
Team
Matthew Fidler
MaintainerShow author detailsDirk Eddelbuettel
Yuan Xiong
Show author detailsRolesAuthorMirjam Trame
Show author detailsRolesContributorRichard Hooijmaijers
Show author detailsRolesAuthorMarc Lavielle
Show author detailsRolesContributorBen Goodrich
Show author detailsRolesContributorDavid Ardia
Show author detailsRolesCopyright holderHadley Wickham
Show author detailsRolesContributorEmmanuelle Comets
Show author detailsRolesContributorRik Schoemaker
Justin Wilkins
Robert Leary
Show author detailsRolesContributorRobert B. Schnabel
Show author detailsRolesContributorVipul Mann
Show author detailsRolesAuthorJohannes Pfeifer
Show author detailsRolesContributorMason McComb
Elizabeth Eskow
Show author detailsRolesContributorWenping Wang
Show author detailsRolesAuthorMahmoud Abdelwahab
Show author detailsRolesContributorAudrey Lavenu
Show author detailsRolesContributorTeun Post
Show author detailsRolesContributorKatharine Mullen
Show author detailsRolesCopyright holder
Insights
Last 30 days
This package has been downloaded 1,249 times in the last 30 days. That's enough downloads to impress a room full of undergrads. A commendable achievement indeed. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 46 times.
The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.
Last 365 days
This package has been downloaded 18,879 times in the last 365 days. The academic equivalent of having a dedicated subreddit. There are fans, and maybe even a few trolls! The day with the most downloads was Feb 19, 2025 with 177 downloads.
The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.
Data provided by CRAN
Binaries
Dependencies
- Depends1 package
- Imports15 packages
- Suggests17 packages
- Linking To8 packages
- Reverse Imports7 packages