nlmixr2est

Nonlinear Mixed Effects Models in Population PK/PD, Estimation Routines

CRAN Package

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 ). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 ).


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  • Depends2 packages
  • Imports18 packages
  • Suggests17 packages
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