nph

Piecewise constant hazard functions are used to flexibly model survival distributions with non-proportional hazards and to simulate data from the specified distributions. A function to calculate weighted log-rank tests for the comparison of two hazard functions is included. Also, a function to calculate a test using the maximum of a set of test statistics from weighted log-rank tests (MaxCombo test) is provided. This test utilizes the asymptotic multivariate normal joint distribution of the separate test statistics. The correlation is estimated from the data. These methods are described in Ristl et al. (2021) doi:10.1002/pst.2062. Finally, a function is provided for the estimation and inferential statistics of various parameters that quantify the difference between two survival curves. Eligible parameters are differences in survival probabilities, log survival probabilities, complementary log log (cloglog) transformed survival probabilities, quantiles of the survival functions, log transformed quantiles, restricted mean survival times, as well as an average hazard ratio, the Cox model score statistic (logrank statistic), and the Cox-model hazard ratio. Adjustments for multiple testing and simultaneous confidence intervals are calculated using a multivariate normal approximation to the set of selected parameters.

Last 30 days

This package has been downloaded 260 times in the last 30 days. Enough downloads to make a small wave in the niche community. The curiosity is spreading! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 12 times.

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Last 365 days

This package has been downloaded 4,649 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Jun 04, 2024 with 962 downloads.

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