reflimR

Uses an indirect method based on truncated quantile-quantile plots to estimate reference limits from routine laboratory data. The principle of the method was developed by Robert G Hoffmann (1963) doi:10.1001/jama.1963.03060110068020 and modified by Georg Hoffmann and colleagues (2015) doi:10.1515/labmed-2015-0104, (2020) doi:10.1515/labmed-2020-0005, and (2022) doi:10.1007/978-3-031-15509-3_31.

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