replicateBE

Average Bioequivalence with Expanding Limits (ABEL)

CRAN Package

Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' / 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well.

  • Version1.1.3
  • R version≥ 3.5.0
  • LicenseGPL (≥ 3)
  • Needs compilation?No
  • Last release05/02/2022

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  • Depends1 package
  • Imports7 packages
  • Suggests4 packages