scoper

Spectral Clustering-Based Method for Identifying B Cell Clones

CRAN Package

Provides a computational framework for identification of B cell clones from Adaptive Immune Receptor Repertoire sequencing (AIRR-Seq) data. Three main functions are included (identicalClones, hierarchicalClones, and spectralClones) that perform clustering among sequences of BCRs/IGs (B cell receptors/immunoglobulins) which share the same V gene, J gene and junction length. Nouri N and Kleinstein SH (2018) doi:10.1093/bioinformatics/bty235. Nouri N and Kleinstein SH (2019) doi:10.1101/788620. Gupta NT, et al. (2017) doi:10.4049/jimmunol.1601850.


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