sctransform

Variance Stabilizing Transformations for Single Cell UMI Data

CRAN Package

A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija (2019) doi:10.1186/s13059-019-1874-1, and Choudhary and Satija (2022) doi:10.1186/s13059-021-02584-9 for more details.


Documentation


Team


Insights

Last 30 days

This package has been downloaded 28,276 times in the last 30 days. The downloads are officially high enough to crash an underfunded departmental server. Quite an accomplishment! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 1,109 times.

Sun
Mon
Tue
Wed
Thu
Fri
Sat
0 downloadsMar 2, 2025
1,019 downloadsMar 3, 2025
1,177 downloadsMar 4, 2025
1,191 downloadsMar 5, 2025
1,199 downloadsMar 6, 2025
1,009 downloadsMar 7, 2025
565 downloadsMar 8, 2025
506 downloadsMar 9, 2025
1,021 downloadsMar 10, 2025
1,104 downloadsMar 11, 2025
1,017 downloadsMar 12, 2025
1,263 downloadsMar 13, 2025
943 downloadsMar 14, 2025
470 downloadsMar 15, 2025
438 downloadsMar 16, 2025
1,088 downloadsMar 17, 2025
1,289 downloadsMar 18, 2025
1,173 downloadsMar 19, 2025
1,125 downloadsMar 20, 2025
876 downloadsMar 21, 2025
447 downloadsMar 22, 2025
393 downloadsMar 23, 2025
1,230 downloadsMar 24, 2025
1,259 downloadsMar 25, 2025
1,457 downloadsMar 26, 2025
1,075 downloadsMar 27, 2025
910 downloadsMar 28, 2025
475 downloadsMar 29, 2025
423 downloadsMar 30, 2025
1,025 downloadsMar 31, 2025
1,109 downloadsApr 1, 2025
0 downloadsApr 2, 2025
0 downloadsApr 3, 2025
0 downloadsApr 4, 2025
0 downloadsApr 5, 2025
393
1,457

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 322,311 times in the last 365 days. This is the kind of download count that makes grant committees nod approvingly. A job well done, even the stoic reviewers might be impressed! The day with the most downloads was Feb 12, 2025 with 2,714 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Imports11 packages
  • Suggests3 packages
  • Linking To2 packages
  • Reverse Imports1 package
  • Reverse Suggests4 packages