sctransform

Variance Stabilizing Transformations for Single Cell UMI Data

CRAN Package

A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija (2019) , and Choudhary and Satija (2022) for more details.


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  • Depends1 package
  • Imports11 packages
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