simIDM

Simulating Oncology Trials using an Illness-Death Model

CRAN Package

Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) doi:10.1002/sim.8295. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated.


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Last 30 days

This package has been downloaded 180 times in the last 30 days. Now we're getting somewhere! Enough downloads to populate a lively group chat. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 7 times.

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0 downloadsMar 2, 2025
3 downloadsMar 3, 2025
9 downloadsMar 4, 2025
8 downloadsMar 5, 2025
4 downloadsMar 6, 2025
3 downloadsMar 7, 2025
6 downloadsMar 8, 2025
1 downloadsMar 9, 2025
5 downloadsMar 10, 2025
6 downloadsMar 11, 2025
6 downloadsMar 12, 2025
8 downloadsMar 13, 2025
6 downloadsMar 14, 2025
6 downloadsMar 15, 2025
7 downloadsMar 16, 2025
2 downloadsMar 17, 2025
10 downloadsMar 18, 2025
7 downloadsMar 19, 2025
10 downloadsMar 20, 2025
7 downloadsMar 21, 2025
6 downloadsMar 22, 2025
2 downloadsMar 23, 2025
8 downloadsMar 24, 2025
4 downloadsMar 25, 2025
10 downloadsMar 26, 2025
5 downloadsMar 27, 2025
8 downloadsMar 28, 2025
2 downloadsMar 29, 2025
10 downloadsMar 30, 2025
4 downloadsMar 31, 2025
7 downloadsApr 1, 2025
0 downloadsApr 2, 2025
0 downloadsApr 3, 2025
0 downloadsApr 4, 2025
0 downloadsApr 5, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 2,561 times in the last 365 days. Consider this 'mid-tier influencer' status—if it were a TikTok, it would get a nod from nieces and nephews. The day with the most downloads was Jul 21, 2024 with 78 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


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Dependencies

  • Imports6 packages
  • Suggests7 packages