simtrial
Clinical Trial Simulation
Provides some basic routines for simulating a clinical trial. The primary intent is to provide some tools to generate trial simulations for trials with time to event outcomes. Piecewise exponential failure rates and piecewise constant enrollment rates are the underlying mechanism used to simulate a broad range of scenarios such as those presented in Lin et al. (2020) doi:10.1080/19466315.2019.1697738. However, the basic generation of data is done using pipes to allow maximum flexibility for users to meet different needs.
- Version0.4.2
- R versionunknown
- LicenseGPL-3
- Needs compilation?Yes
- Last release11/18/2024
Documentation
- VignetteApproximating an arbitrary hazard function
- VignetteComputing p-values for Fleming-Harrington weighted logrank tests and the MaxCombo test
- VignetteUsing the Magirr-Burman weights for testing
- VignetteSimulating time-to-event trials in parallel
- VignetteRestricted mean survival time (RMST)
- VignetteBasic tools for time-to-event trial simulation and testing
- VignetteTTE simulation data manipulations
- MaterialREADME
- MaterialNEWS
Team
Yujie Zhao
Yalin Zhu
Show author detailsRolesContributorHeng Zhou
Show author detailsRolesContributorNan Xiao
Show author detailsRolesContributorJohn Blischak
Show author detailsRolesContributorKeaven Anderson
Show author detailsRolesAuthorYilong Zhang
Show author detailsRolesAuthorXintong Li
Jianxiao Yang
Show author detailsRolesContributorMerck & Co., Inc., Rahway, NJ, USA and its affiliates
Show author detailsRolesCopyright holderAmin Shirazi
Show author detailsRolesContributorRuixue Wang
Show author detailsRolesContributorYi Cui
Show author detailsRolesContributorPing Yang
Show author detailsRolesContributorLili Ling
Show author detailsRolesContributorCole Manschot
Show author detailsRolesContributor
Insights
Last 30 days
This package has been downloaded 634 times in the last 30 days. Not bad! The download count is somewhere between 'small-town buzz' and 'moderate academic conference'. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 12 times.
The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.
Last 365 days
This package has been downloaded 8,362 times in the last 365 days. A solid achievement! Enough downloads to get noticed at department meetings. The day with the most downloads was Feb 20, 2025 with 65 downloads.
The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.
Data provided by CRAN
Binaries
Dependencies
- Imports8 packages
- Suggests12 packages
- Linking To1 package
- Reverse Suggests1 package