ssizeRNA

Sample Size Calculation for RNA-Seq Experimental Design

CRAN Package

We propose a procedure for sample size calculation while controlling false discovery rate for RNA-seq experimental design. Our procedure depends on the Voom method proposed for RNA-seq data analysis by Law et al. (2014) doi:10.1186/gb-2014-15-2-r29 and the sample size calculation method proposed for microarray experiments by Liu and Hwang (2007) doi:10.1093/bioinformatics/btl664. We develop a set of functions that calculates appropriate sample sizes for two-sample t-test for RNA-seq experiments with fixed or varied set of parameters. The outputs also contain a plot of power versus sample size, a table of power at different sample sizes, and a table of critical test values at different sample sizes. To install this package, please use 'source("http://bioconductor.org/biocLite.R"); biocLite("ssizeRNA")'. For R version 3.5 or greater, please use 'if(!requireNamespace("BiocManager", quietly = TRUE)){install.packages("BiocManager")}; BiocManager::install("ssizeRNA")'.


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Insights

Last 30 days

This package has been downloaded 370 times in the last 30 days. More than a random curiosity, but not quite a blockbuster. Still, it's gaining traction! The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 11 times.

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0 downloadsMar 2, 2025
27 downloadsMar 3, 2025
8 downloadsMar 4, 2025
18 downloadsMar 5, 2025
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44 downloadsMar 17, 2025
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11 downloadsApr 1, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 4,268 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Jul 21, 2024 with 311 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

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Dependencies

  • Imports2 packages
  • Suggests1 package