sumFREGAT

Fast Region-Based Association Tests on Summary Statistics

CRAN Package

An adaptation of classical region/gene-based association analysis techniques to the use of summary statistics (P values and effect sizes) and correlations between genetic variants as input. It is a tool to perform the most popular and efficient gene-based tests using the results of genome-wide association (meta-)analyses without having the original genotypes and phenotypes at hand. See for details: Svishcheva et al (2019) Gene-based association tests using GWAS summary statistics. Bioinformatics. Belonogova et al (2022) SumSTAAR: A flexible framework for gene-based association studies using GWAS summary statistics. PLOS Comp Biol.

  • Version1.2.5
  • R versionunknown
  • LicenseGPL-3
  • Needs compilation?Yes
  • Last release06/07/2022

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  • Imports3 packages
  • Suggests1 package