titeIR

Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities

CRAN Package

Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.

  • Version0.1.0
  • R versionunknown
  • LicenseGPL-3
  • Needs compilation?No
  • Last release09/28/2018

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  • Imports1 package